Oct 2026
Sciadonic acid ameliorates cognitive impairment in APP/PS1 mice with concomitant modulation of gut microbiota and brain metabolism.
Oral SCA administration to APP/PS1 transgenic mice significantly improved spatial learning and memory and suppressed pro-inflammatory cytokines, and was associated with cognitive and neuropathological improvements alongside alterations in gut microbiota and hippocampal metabolism.
Shu-Juan Xie, Bo Zheng, Ming-Qian Li et al.
· Food & Function · 0 citations