Xing-Xu Huang

Longitudinal Characterization of Giant ANK2-Depleted Monkeys Suggests Neurodevelopmental-Disorder-Like Phenotypes

The ANK2 gene mutations are marked risk factors for autism spectrum disorder, one of the neurodevelopmental disorders (NDDs) that often extends into adulthood and has a complex etiology involving genetic and environmental factors. ANK2 encodes 2 major isoforms, AnkB-220 (220-kDa isoform of ankyrin-B) and giant AnkB-440...