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Author

Xing-Yi Wang

2 papers indexed here

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Open access Sep 2026

Hypertriglyceridemia and atherosclerosis in Apolipoprotein A5 mutant rabbits generated using CRISPR/Cas9.

ApolipoproteinA5 (APOA5) plays an important role in regulating plasma triglycerides (TG). Most in vivo data, however, derive from murine models whose lipoprotein metabolism diverges substantially from humans, and no rabbit APOA5 loss-of-function model has previously been described. Microinjection of Cas9 mRNA and two e...

Yi-Wen Zha, Lin-Ling Feng, Ting Zhang et al. · 0 citations
Review Open access Sep 2026

Therapeutic Targeting of Tauopathies: From Druggable Biology to Precision Intervention.

Tauopathies encompass a heterogeneous group of neurodegenerative disorders characterized by the transition of tau from a microtubule-stabilizing protein into pathogenic, seed-competent species. Increasing evidence has redefined tau from a descriptive pathological hallmark to a pharmacologically actionable target across...

Cheng-Jia Zhang, Jia-Liang Ma, Xin-Ruo Wu et al. · 0 citations

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