Author

Xinhe Ma

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Review Open access Aug 2026

Recent Advances (2020–2025) in Estrogen and ER-Positive Breast Cancer: Receptor Signaling, Tumor Microenvironment, Endocrine Therapy Resistance and Innovative Treatment Strategies—A Comprehensive Review

This comprehensive review systematically summarizes high-quality literature published from 2020 to 2025, focusing on estrogen biosynthesis and metabolic dysregulation, dual genomic/non-genomic estrogen receptor signaling mediated by ERα, ERβ and GPER1, epigenetic regulatory networks, and bidirectional crosstalk between...

Jia-Xin Zhao, Donghai Li, Shao-Feng Yang et al. · Cancer Management and Resear... · 0 citations

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