Open access
Aug 2026
Integrative multi-omics identifies cholangiolocarcinoma as a distinct molecular subtype of intrahepatic cholangiocarcinoma.
BACKGROUND & AIMS Intrahepatic cholangiocarcinoma (iCCA) exhibits profound heterogeneity, complicating its clinical management. This study aims to define the molecular features underlying its histological subtypes to better understand their biology and identify potential therapeutic opportunities. METHODS We performe...
Jun Chen, Xuan Gao, Tian-Li Chen et al.
· JHEP Reports · 0 citations