Xinjie Liu

High–spatiotemporal resolution deuterium metabolic imaging enables in vivo phenotyping of intra- and intertumoral heterogeneity

In vivo DMI data acquired with sufficiently high spatiotemporal resolution can distinguish metabolically distinct subregions within viable tumors and between tumor models, demonstrating that in vivo DMI-based metabolic maps could provide the means to characterize intra- and intertumoral heterogeneities.