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Xinxin Liang

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2 papers indexed here

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Review Open access 2026

RAD51 in homologous recombination-mediated DNA damage repair and genome stability: Mechanisms, regulation and implications for disease

Homologous recombination (HR) is a high-fidelity DNA repair pathway that preserves genome stability through the accurate repair of DNA double-strand breaks. RAD51 is the central recombinase of HR and catalyzes the key processes of homology search and strand invasion through the formation of nucleoprotein filaments on s...

Tao Zhou, Yilin Cui, Xinxin Liang et al. · 0 citations
Open access Aug 2026

A regulatory adaptor for RAD51's AAA+ unfoldase promotes homologous recombination-mediated DNA repair and genome stability.

DNA double-strand breaks, including those arising from DNA interstrand crosslinks, are highly cytotoxic forms of DNA damage. Their precise repair by homologous recombination (HR) is essential for maintaining genomic stability. During HR, timely disassembly of the core machinery, RAD51 nucleoprotein filaments, is critic...

Tao Zhou, Ming Pang, Xinxin Liang et al. · 0 citations

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