Open access
Aug 2026
Lactate promotes liver regeneration by increasing fatty acid oxidation through GCN5-mediated H3K9 lactylation.
BACKGROUND & AIMS Lactylation has been implicated in the repair and regeneration of multiple organs including skin and heart. The liver serves as a vital organ for lactate metabolism, while the roles of lactate and lactylation during liver regeneration remain unclear. METHODS Mice were subjected to 70% partial hepate...
Xun Qiu, Hanzhi Xu, Lijun Meng et al.
· Cellular and Molecular Gastr... · 0 citations