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Xin-Yu Duan

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Aug 2026

Ground-State Flavin-Dependent Enzymatic Catalysis for Formal Hydrophosphinylation of Alkenes.

Organophosphorus compounds constitute an important class of functional molecules with broad relevance in synthesis, catalysis, and medicinal chemistry. Despite their importance, biocatalytic C-P bond formation remains rare, with only a limited number of examples identified from natural product biosynthesis. Here we rep...

Duo Zhang, Chentao Liu, Kang Yin et al. · 0 citations
Open access Jul 2026

A biocatalytic platform for the stereoselective synthesis of diverse atropisomeric compounds using engineered metalloenzymes

Atropisomeric compounds are widely distributed in natural products and pharmaceuticals and serve as key scaffolds in asymmetric catalysis. Despite their remarkable structural diversity, current synthetic efforts have primarily focused on C–C biaryl atropisomers, while the synthesis of other classes of atropisomeric com...

Xiaochen Cai, Dong Cui, Yuchen Chu et al. · 0 citations

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