Ocular topical aesculetin delivery via VA64/TPGS co-assembled micelles for redox-inflammatory modulation in selenite-induced cataract.
Cataract progression is closely associated with oxidative stress and inflammatory activation, while effective non-surgical interventions remain limited. Aesculetin (AES) possesses antioxidant and anti-inflammatory activities, but its topical ophthalmic application is restricted by poor aqueous solubility, insufficient...