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Xinyuan Liao

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Open access Jul 2026

IVT-free, chemically synthesized protein-encoding RNA oligonucleotides for rapid production of personalized cancer vaccines

A cap-independent translation enhancer BBV is introduced and protein-encoding RNA oligonucleotides (PEOs) are developed, chemically synthesized RNAs bearing 5’-OH and 3’-P termini that drive rolling circle translation after endogenous circularization that built an IVT-free platform for rapid, safe, and highly druggable...

Qian Pan, Chi Zhang, Xin-Yue Wang et al. · 0 citations

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