Author

Xin-Yue Liu

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Review Open access Aug 2026

Multi-omics insights into the mechanisms and prognosis of IPF

Idiopathic pulmonary fibrosis (IPF) represents another progressive and devastating interstitial lung disease found across populations, with a prominent male predominance accounting for approximately 70% of cases. Regional variation in IPF-related genetic polymorphisms, especially in the Americas, Europe, and Asia, poin...

Dong-Lu Chen, Qian-Wei Chen, Hong-Hui Liu et al. · Genes and Environment · 0 citations

Jul 2026

Functional noncoding variants within the TBX1 enhancer contribute to tetralogy of Fallot.

This study demonstrates the involvement of noncoding variants in the TBX1 enhancer in TOF pathogenesis, highlighting the feasibility of using organoids to decipher the underlying mechanisms of unconserved noncoding regions in developmental malformations.

Jimiao Gao, T. Jiang, Yingyi Quan et al. · Science China Life Sciences · 0 citations