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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Xinyue Zhang

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2 papers indexed here

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Open access Sep 2026

Structure based discovery of antipsychotic-like TAAR1 agonists

Fourteen TAAR1 agonists emerge with high brain exposure and potencies, with one compound showing potency comparable to the investigational drug ulotaront and two compounds exhibiting even greater potency, at levels sufficient for behavioral studies.

Si-Jie Huang, Heng Liu, Yu-Jin Wu et al. · 0 citations
Open access Jul 2026

Molecular principles for graded activation of dopamine D1 receptor

G protein-coupled receptors (GPCRs) signal across a continuum of activation states, yet how ligands encode distinct signaling efficacies remains poorly understood. Here, we define the molecular mechanism underlying graded activation of the dopamine D1 receptor (D1R), a major therapeutic target for neuropsychiatric diso...

Xinyue Zhang, Yu Zheng, Heng Liu et al. · 0 citations

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