Reciprocal Coupling among Extracellular Matrix Mechanics, Mechanosensitive Ion Channels, and Cell Remodeling Behaviors.
This review discusses the close interplay among ECM mechanics, mechanosensitive ion channels, and cell remodeling behaviors, with particular emphasis on ion channels as mechanochemical control nodes that connect material-defined mechanical cues to cytoskeletal tension, adhesion dynamics, and transcriptional reprogrammi...