Combined PM2.5 and microplastics exposure exacerbates allergic asthma via OPA1/SLC7A11-mediated airway epithelial ferroptosis.
This study aimed to investigate whether PM2.5 and microplastics (MPs) aggravate ovalbumin (OVA)-induced allergic airway injury and to elucidate the role of mitochondrial dysfunction-associated ferroptosis in this process. An OVA-induced murine asthma model and OVA-stimulated MRE cells were established and exposed to PM...