Despite advances in traditional therapies, the global burden of malignant tumors remains substantial. Although immunotherapy has achieved remarkable breakthroughs by activating the host immune system, its clinical benefits are limited to a subset of patientsowing to low response rates and drug resistance. Emerging evid...
Hao-Juan Feng, Xiu-Juan Huang, Yong-Ju Zhuang et al.· Frontiers in Immunology· 0 citations
Sepsis is a life-threatening syndrome driven by a dysregulated host response to infection, characterised by dynamic and overlapping phases of hyperinflammation and immune suppression. Despite advances in critical care, effective immunomodulatory therapies remain lacking, reflecting an incomplete understanding of its co...
Hai-Long Yan, Lin-Tong Ma, Xiu-Juan Huang et al.· Frontiers in Immunology· 0 citations
Pan-cancer analysis establishes WDR76 as a robust pan-cancer prognostic biomarker and a potential immunotherapeutic target and provides experimental evidence that WDR76 functions as an oncogenic driver in liver cancer, promoting malignant phenotypes and offering a novel avenue for targeted therapeutic intervention.
Yi-Fan Wang, Rong Zhou, Shen-Long Guo et al.· International Journal of Imm...· 0 citations
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