RNF180 loss stabilizes BCAS4 to enhance PD-L1 expression and immune evasion in hepatocellular carcinoma
Summary Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, and the regulation of immune evasion within the tumor microenvironment remains poorly understood. This study shows that breast carcinoma susceptibility protein 4 (BCAS4), not previously studied in HCC, is markedly upregulat...