Population Pharmacokinetics and Exposure-Response Analysis of Voriconazole in ICU and Non-ICU Hospitalized Adults
Background Voriconazole has marked pharmacokinetic variability and a narrow therapeutic window, making individualized dosing difficult. Published population pharmacokinetic (PopPK) models most derive from ICU or general-ward patients, and exposure-response studies are limited. This retrospective study aimed to characte...