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Xu-Dong He

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Open access Sep 2026

FPNuNet: a frequency-aware prompt-guided network for nuclear segmentation and classification in immunohistochemistry images

Abstract Background Accurate nuclear segmentation and classification (NuSC) in immunohistochemistry (IHC)-stained whole-slide images is essential for reliable biomarker quantification in computational pathology. Although existing NuSC methods perform well on Hematoxylin and Eosin images, they frequently underperform on...

Lu-Lu Qin, Zhi-Gang Pei, Xu-Dong He et al. · 0 citations

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