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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xu-Dong Jiao

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Open access Oct 2026

OT-CATH, a conserved antimicrobial peptide in Otariidae species, exhibits potent activity against gram-negative bacteria

ABSTRACT The rapid emergence of multidrug-resistant gram-negative bacteria necessitates the development of effective antimicrobial agents to combat antimicrobial resistance. Here, we identified and characterized OT-CATH, a conserved cathelicidin-family antimicrobial peptide derived from Otariidae species. OT-CATH exhib...

Yi-Xiao Song, Yu-Feng Ren, Juan Wang et al. · 0 citations
Jul 2026

Screening of Cell-Penetrating Peptides To Enhance the Therapeutic Efficacy of α-Helical Antimicrobial Peptides against Intracellular Bacterial Infections.

It is highlighted that cationic or amphipathic CPPs, particularly those with intrinsic antimicrobial activity and high positive charge, can enhance the anti-infective performance of HC1-based conjugates in this context.

Shuangyu Li, W. Hao, Zifan Ye et al. · 0 citations

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