Rational Engineering of Hemicellulose-based Nanocarriers for Precision Biomedicine: A Critical Review of Molecular Structure, Nanocarrier Properties, and Biomedical Performance.
Hemicellulose, the second-most-abundant biopolymer on Earth, offers a renewable platform for nanomedicine due to its tunable branching chemistry, biocompatibility, and amphiphilic self-assembly. However, clinical translation of hemicellulose-based nanoparticles remains stalled due to the absence of quantitative design...