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Author

Xu-Lei Dai

2 papers indexed here

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Open access Sep 2026

Obesity Increases Atherosclerosis Susceptibility via an Intertissue miR-30e-SLC7A11 Axis.

BACKGROUND With obesity as a risk factor for atherosclerotic disease, recent research suggests that adipose tissue in obese animal models and humans can generate endocrine-like molecules that affect arterial health. Previous studies showed that microRNA-30e (miR-30e) levels are elevated in atherosclerosis and solute ca...

Chen Wang, Jian-Qing She, Xiaoli Qian et al. · 0 citations
Aug 2026

Hepatic MED1 disruption ameliorates obesity-related fatty liver by attenuating SREBP1-driven lipogenesis.

BACKGROUND & AIMS Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major global health concern, with obesity serving as a primary risk factor. Although Mediator subunit 1 (MED1) plays an important role in lipid metabolism, its specific contribution to obesity-related hepatic steatosis remains uncle...

Xu-Lei Dai, Zi-Yue Wang, Xiang-Zhu Xiao et al. · 0 citations

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