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UFMylation of SHBs increases protein stability by antagonizing ubiquitination and promotes virion production
ABSTRACT Post-translational modifications orchestrate virus–host interactions, yet their roles in the hepatitis B virus (HBV) life cycle remain incompletely defined. The small hepatitis B surface antigen (SHBs)—the most abundant HBV protein—drives immune evasion, pathogenesis, and virion/subviral particle (SVP) product...
Epstein-Barr virus-encoded microRNA-BART17-5p suppresses cell proliferation and metastasis by targeting CERK
Epstein-Barr virus (EBV) is an oncogenic DNA virus that is etiologically associated with multiple malignancies, including nasopharyngeal carcinoma, gastric carcinoma, and lymphomas. Although EBV encodes numerous viral microRNAs (miRNAs), the pathogenic functions of individual miRNAs remain incompletely characterized. I...