Aug 2026
Extracellular vesicles carrying the tenascin-C protein participate in glucose metabolism in neurodegenerative injury via inhibiting the AKT/GLUT1 pathway.
It is shown that EVs released by microglia exposed to 40 μM paraquat are internalized by dopaminergic neurons, where they impair glucose metabolism and induce neurodegenerative injury through the intercellular transfer of tenascin-C (TNC).
Xu Liu, Ling-Fang Chen, Xue-Dong Zhu et al.
· Chemico-Biological Interacti... · 0 citations