Atypical Cortical Asymmetries in Toddlers with Congenital Heart Disease Before Surgery.
Mild and moderate-severe CHD groups showed comparable alterations in cerebral asymmetries, predominantly involving perisylvian and default-mode network regions.
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Mild and moderate-severe CHD groups showed comparable alterations in cerebral asymmetries, predominantly involving perisylvian and default-mode network regions.
This study demonstrates the involvement of noncoding variants in the TBX1 enhancer in TOF pathogenesis, highlighting the feasibility of using organoids to decipher the underlying mechanisms of unconserved noncoding regions in developmental malformations.
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