Xu-Ming Zhang

A review of advances in research on mechanisms inhibiting kidney stone formation from a network pharmacology perspective

Nephrolithiasis is a prevalent, highly recurrent urological disorder affecting 1%–15% of the global population, with 5-year recurrence rates reaching up to 50%. While surgical interventions achieve acute stone clearance, they do not resolve underlying metabolic derangements, crystal-induced tubular injury, or chronic i...