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Xu-Wei Wu

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Open access Sep 2026

α-aminobutyric acid promotes tumor progression by polarizing macrophages through the ASNS-mTORC2 axis.

These findings uncover α-aminobutyric acid as a previously unrecognized signaling metabolite to control TAM polarization, providing insights into the metabolic crosstalk within the TME and offering a potential therapeutic target to improve cancer immunotherapy outcomes.

Fei Li, Xiao-Rong Xie, Tong-Ran Xu et al. · 0 citations

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