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Xuanrong Sun

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Oct 2026

Bioorthogonal Assembly of Cell-Nanoparticle Hybrids Enables Synergistic Cancer Therapy

Integrating nanoparticles (NPs) with living cells into a unified therapeutic system remains a major methodological challenge. Here, we describe a robust and modular bioorthogonal strategy for constructing cell-nanoparticle hybrids (CNHs) via sequential thiazolidine formation and SpyCatcher/SpyTag ligation. This two-s...

Yu-Teng Chu, Yuan Chen, Xiu-Zhi Xie et al. · 0 citations
Jul 2026

Soluplus®-based solid dispersion enhances oral bioavailability of A10: a cGAS-STING and ICD activator for bladder cancer therapy.

Evidence of the immune activation induced by A10 against BCa T24 cells is provided, and A10 could activate the cGAS-STING pathway, promote DAMPs release, and induce Immunogenic Cell Death (ICD) for anti-tumor activity against BCa cells in vitro.

Wenchao Wang, F. Dong, Junrong Lei et al. · 0 citations

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