TraSPIN: inferring transporter specificity through language model-guided graph learning
Membrane transporters mediate cellular chemical exchange, yet their substrate specificities remain poorly characterized, with experimental studies constrained by the instability of membrane proteins. Existing computational tools often target narrow substrate classes or fail to generalize to distant homologs. We present...
Tong Pan, Jie Liu, Jing Xu et al.
· Genome biology · 0 citations