Smart Implant Coating with Pathological-Microenvironment-Driven Drug and Nanozyme Delivery for Osteoporotic Bone Healing.
Stimuli-responsive drug delivery from orthopedic implants holds particular promise for enhancing osseointegration in osteoporotic bone. However, challenges such as the lack of feedback-regulated functionality and microenvironmental modulation persist. Here, we developed an osteoporotic microenvironment-responsive impla...