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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

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Xue-Bing Wu

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Open access Sep 2026

CasNano: An ultracompact CRISPR-Cas12f with a GC-rich PAM for epigenome editing with therapeutic potential

Clinical use of CRISPR-Cas proteins for genome engineering is constrained by their large size, limiting in vivo delivery. To address this, we engineered an ultracompact and versatile platform from a minimally active, 400-amino acid Cas12f protein from Blautia lenta. A multi-stage strategy of structure-guided protein mu...

Dongkyeong Kim, Chia-Wei Huang, Richard Pan et al. · 0 citations
Review Open access Aug 2026

A New Option for the Management of Dyslipidemias: Advances in Research on the Small Interfering RNA Drug Inclisiran

Inclisiran may represent another milestone in the treatment of dyslipidemia, and the associated mechanism of action, pharmacology, clinical trial data, efficacy, safety, use in special populations, and adverse effects are comprehensively discussed.

Xue-Bing Wu, Jing Zhang · 0 citations

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