Author

Xue Chen

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Open access Sep 2026

Multi-Organ Per- and Polyfluoroalkyl Substances Accumulation Reveals Brain-Peripheral Metabolic Coupling and Glucocorticoid-Related Dysregulation in Mice.

Per- and polyfluoroalkyl substances (PFASs) are persistent synthetic chemicals increasingly linked to systemic metabolic dysregulation and potential Alzheimer's disease (AD) risk. However, whether chronic PFASs exposure disrupts metabolic crosstalk between peripheral organs and the brain remains unclear. This study aim...

Jin-Yue Zhou, Xue Chen, H. Hong et al. · Environmental Pollution · 0 citations

Open access Oct 2026

Integrated Multi-Omics Analysis Reveals ACO2 as an Oxidative-Stress-Related Biomarker in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory impairment. Oxidative stress plays an important role in disease progression in AD. However, the molecular mechanisms underlying oxidative stress in AD remain unclear and reliable biomarkers for its detecti...

Wen-Bo Dou, Xue Chen, H. Hong et al. · Biomolecules · 0 citations