Author

Xue Hu

2 papers indexed here

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Open access Aug 2026

A multimodal analysis suggests partial IRF8/TLR7-associated myeloid transcriptional convergence between diabetic kidney disease and Parkinson’s disease

Background Diabetic kidney disease (DKD) and Parkinson’s disease (PD) affect different organs but share epidemiological associations and innate immune abnormalities. The extent and cellular basis of reproducible cross-disease transcriptomic convergence remain uncertain. Methods Two DKD glomerular and three PD substanti...

Xue Hu, Ying-Zhuo Li, Bo-Sheng Luo et al. · PLoS ONE · 0 citations

Open access Jul 2026

Aging-driven transcriptional programs in diabetic kidney disease: multi-omics discovery of diagnostic biomarkers and drug-repurposing targets.

This study identified age-related hub genes, constructed a reliable diagnostic signature, and suggested SYK-fostamatinib and APOC3-selexipag as potential drug-repurposing candidates for DKD, which requires further experimental and clinical validation.

Xue Hu, Yingzhuo Li, Yang Wang et al. · Clinical Epigenetics · 0 citations