Open access
Oct 2026
Activation of CaMKIIα regulates hippocampal mitochondrial metabolism and attenuates neuroinflammation: A novel therapeutic target for obesity-associated neurocognitive disorders.
ABSTRACT Obesity is strongly associated with cognitive impairment, especially in memory. However, the underlying molecular mechanisms remain unclear. Ca2+/calmodulin-dependent protein kinase II (CaMKII), a key synaptic kinase, regulates synaptic plasticity and hippocampal memory function through N-methyl-D-aspartate re...
Fan Liu, Chen Chen, Yu-Bing Zeng et al.
· Neural Regeneration Research · 0 citations