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Author

Xue-Li Chen

2 papers indexed here

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Open access Oct 2026

AbRefine: Framework-Conditioned Refinement for Structure-Guided Antibody CDR Design

Structure-guided antibody CDR design constrains residue selection using backbone geometry, but structural evidence alone may leave multiple amino acids plausible. We investigate whether the fixed antibody framework provides complementary sequence information for resolving this ambiguity. We introduce AbRefine, an infor...

Qi Liu, Xin-Yi Xu, Qian Cheng et al. · 0 citations
Sep 2026

Zoomable dual-channel NIR-I/II fluorescence mesoscopy for in vivo characterization.

A zoomable dual-channel NIR-I/II fluorescence mesoscopic imaging system that bridges macroscopic and microscopic scales via seamless zooming is developed and validated for comprehensive hepatobiliary disease diagnosis using a cholestatic liver injury model.

Xin-Yu Wang, Dai-Fang Xu, Zhao-Yang Cheng et al. · 0 citations

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