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Xue-Ling Bai

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Open access Sep 2026

HMGB1 induces mitochondrial dysfunction through the TLR4 and RAGE pathways to promote astrocyte autophagy and PANoptosis in intracerebral hemorrhage.

BACKGROUND Secondary injury is an important factor that leads to a poor prognosis of intracerebral hemorrhage (ICH). Programmed cell death (PCD) plays an important role in secondary injury. After ICH, hyperactivated astrocytes transition from a protective role to a proinflammatory state, releasing neurotoxic factors th...

Wen-Zuo Shang, Jing-Yu Cui, Xue-Ling Bai et al. · 0 citations

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