Open access
Sep 2026
A fungal-derived benzothiazole derivative overcomes osimertinib resistance in NSCLC by targeting SCD1
6-(2-hydroxyethyl) benzo[d]thiazol-4-ol (HBT) is identified as a promising therapeutic candidate for overcoming osimertinib resistance in NSCLC and SCD1 is suggested as a potential target for combating such resistance.
Bo-Yin Li, Yuan-Yu Ke, Jin-Hua Zhu et al.
· Natural Products and Biopros... · 0 citations