Open access
Aug 2026
Brucella deploys multiple type IV effectors that simultaneously control bacterial survival and host inflammatory cell death
ABSTRACT The type IV secretion system (T4SS) acts as the central virulence determinant of Brucella, facilitating intracellular survival via the secretion of effector proteins. In this study, we combined bioinformatic prediction with translocation assays to identify seven novel VirB-dependent effectors. Functional chara...
Dongjie Sun, Meng-Tao Zhang, Yifan Wu et al.
· Virulence · 0 citations