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Xue-Zhi Liu

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Review Open access Sep 2026

Macrophage immunometabolic reprogramming in inflammatory repair failure in osteonecrosis of the femoral head

The classical “vascular occlusion” model does not fully account for osteonecrosis of the femoral head (ONFH). Femoral head collapse may progress despite restored perfusion, and ischemia alone cannot adequately explain steroid-associated ONFH. We propose that ONFH involves disruption of bone-vascular-immune homeostasis,...

Yan Wang, Lu-Lu Zhang, Xue-Zhi Liu et al. · 0 citations
Review Open access Sep 2026

Mechanistic interactions of diet, exercise, and pharmacotherapy in skeletal muscle metabolism: evidence and translational perspectives

Skeletal muscle plays a central role in whole-body energy homeostasis, metabolic flexibility, and insulin sensitivity, acting as a key integrator of nutritional, mechanical, and pharmacological signals. Although diet, exercise, and pharmacotherapy are often investigated as separate interventions, they converge on share...

Yan Wang, Meng-Ran Qin, Xue-Zhi Liu et al. · 0 citations

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