Review
Open access
Jul 2026
Base editing for precision therapeutics.
Key remaining challenges include bystander editing within the activity window, residual off-target DNA and RNA editing, delivery constraints, delivery constraints, immunogenicity, and the need for durable long-term safety evidence across relevant cell types and disease contexts.
Moksada Regmi, K. Ma, C. Bi et al.
· Cell Genomics · 0 citations