Open access
Jul 2026
Treatment effects on sphingosine-1-phosphate and its receptors in major depressive disorder: implications for biomarkers
The data demonstrate a significant, sex-dependent dysregulation of the peripheral S1P signaling pathway in MDD, which is responsive to antidepressant treatment, implying that the S1P pathway plays a crucial role in the pathophysiology of depression.
Xiao Yang, Le Wang, A. Jiang et al.
· BMC Psychiatry · 0 citations