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Jul 2026

Chebulinic Acid Restores Glycolytic Reprogramming and Mitochondrial Dysfunction in MASLD via Modulation of Lp-PLA2 Signaling.

It is demonstrated that CA improves hepatic metabolic homeostasis through modulation of Lp-PLA2 signaling and significantly ameliorated metabolic dysfunction, hepatic steatosis, inflammation, and oxidative stress in both in vivo and in vitro models.

Yinghui Wang, Guo-Chun Zhang, Xicheng Jiang et al. · 0 citations
Open access Aug 2026

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

The natural flavonoid luteolin is identified as an agent that upregulates METTL7A expression, which subsequently downregulates SLC1A5 expression and inhibits GC progression, and significantly enhances the efficacy of anti‐PD‐1 therapy in GC.

Mingjun Sun, Shuwei Dang, Dazhi Zhou et al. · 0 citations

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