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Xupeng Guo

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Aug 2026

Structure-Guided Engineering of Glycosyltransferase UGT73-327-2 Coupled with UDP-Glucose Regeneration Enables Highly Efficient Biosynthesis of Mogroside VI.

Mogroside VI (Mog VI) is a rare triterpene glycoside from Siraitia grosvenorii with promising bioactivities. However, its biosynthesis is limited by a single rate-limiting glycosylation step converting mogroside V, catalyzed by the inherently low-activity plant glycosyltransferase UGT73-327-2. In this study, we applied...

Dong Guo, Yan Zhang, Xupeng Guo et al. · 0 citations

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