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Open access Aug 2026

Synergistic lethality of combination treatment with Trop2-directed antibody-drug conjugate sacituzumab govitecan and TRAIL agonists in triple negative breast cancer

Dual treatment with SG and TRAIL agonists significantly inhibited tumor growth and caused a borderline significant benefit on survival with no toxicities noted for both drug treatments, suggesting a potential clinical benefit of the combination therapy in TNBC.

Y. Addissie, Y. Greer, Jayakumar R. Nair et al. · 0 citations

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