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Y. Kawaoka

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Open access Aug 2026

Characterisation of a human monoclonal antibody targeting a conserved epitope at the base of the HA head of influenza A(H3N2) virus

Summary Background Numerous broadly reactive human monoclonal antibodies (mAbs) against the haemagglutinin (HA) of influenza A viruses have recognised conserved epitopes across HA subtypes or within subtypes. Most heterosubtypic mAbs target the HA stem, the receptor-binding site (RBS), or the trimeric interface. Althou...

S. Yamayoshi, T. Hamabata, Yuka Inoue et al. · 0 citations
Open access Sep 2026

NGS-RFA/FRA: A High Throughput Experimental and Computational Pipeline for Selective Mutational Scanning in Parallel

The method reduces the timeline required to carry out such assessments with classical methods from about a year to several weeks, and has the potential to greatly enhance surveillance efforts, transforming reactive monitoring into proactive forecasting.

Sina Tureli, T. Bestebroer, S. James et al. · 0 citations
Open access Jul 2026

Isolation and characterization of a clade 2.3.4.4b genotype D1.1 H5N1 virus from dairy cattle in Wisconsin

The isolation and characterization of a clade 2.3.4.4b, genotype D1.1 H5N1 virus from bulk milk collected during a spillover event in Wisconsin in December 2025 highlights the genetic and phenotypic diversity of HPAI H5N1 viruses infecting dairy cattle and underscores the importance of continued surveillance and functi...

Daria Mezhenskaia, Lavanya Babujee, Ai-Lam Lim et al. · 1 citation · ⚡1

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