Acute phosphate-salt exposure is associated with attenuation of the albumin-producing phenotype, HNF4A down-regulation, and ERK activation in HepaRG cells
Under the present acute, supraphysiological exposure conditions, phosphate-salt treatment was associated with attenuation of the albumin-producing phenotype in HepaRG cells, accompanied by HNF4A downregulation and ERK activation, and these findings cannot be attributed specifically to dissolved phosphate.