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Review Open access Sep 2026

Acute phosphate-salt exposure is associated with attenuation of the albumin-producing phenotype, HNF4A down-regulation, and ERK activation in HepaRG cells

Under the present acute, supraphysiological exposure conditions, phosphate-salt treatment was associated with attenuation of the albumin-producing phenotype in HepaRG cells, accompanied by HNF4A downregulation and ERK activation, and these findings cannot be attributed specifically to dissolved phosphate.

Takeshi Honda, Tatsuya Sakaguchi, Y. Kondo et al. · 0 citations

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