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Y. Kou

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Open access Sep 2026

Osteocyte necroptosis drives cortical bone resorption via osteocytic osteolysis in glucocorticoid-induced osteoporosis

Glucocorticoid-induced osteoporosis (GIOP) is characterized by progressive cortical bone fragility accompanied by osteocyte lacunar enlargement and peri-lacunar osteolysis. However, whether these microstructural alterations arise from a specific cell death program remains unclear. Here, we demonstrate that glucocorti...

Xing Rong, Qing-Hua Ren, Y. Kou et al. · 0 citations

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