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Author

Young-Eun Leem

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Open access Sep 2026

Inotodiol prevents age-related muscle wasting by restoring mitochondrial function through liver X receptor beta signaling

Ino treatment significantly improved muscle mass and function in aged mice and prevented dexamethasone (DEX)-induced muscle atrophy and is identified as a promising therapeutic candidate for preserving mitochondrial function and alleviating age-associated muscle dysfunction.

Chang-Lim You, Ju-Hyeon Bae, Yideul Jeong et al. · 0 citations
Open access Aug 2026

Meloxicam protects against muscle and metabolic decline in ageing through Cdon restoration and oxidative stress modulation

Meloxicam (Mcam) is identified as a small molecule inducer of Cdon that enhances myogenic differentiation, increases muscle mass and function in young mice and mitigates age-related muscle atrophy, and is identified as a potential therapeutic target for age-associated skeletal muscle degeneration.

Ju-Hyeon Bae, Hyun-Kyung So, Yideul Jeong et al. · 0 citations

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