Molecular Expression of FGF23 Signaling Components (FGFR1 and α-Klotho) and Their Biochemical Correlation in Early Kidney Impairment
Background: Chronic kidney disease and mineral and bone disorder (CKD-MBD) is associated with dysfunction of the FGF23-FGFR1-a-Klotho signaling pathway involved in phosphate regulation and renal function. Early molecular changes may precede biochemical abnormalities. Objective: This study aimed to determine FGFR1...