Aug 2026
LZTFL1 rewires NADPH-glutathione metabolism to amplify ferroptosis.
Leucine zipper transcription factor-like 1 (LZTFL1) is identified as a key regulator of ferroptosis that rewires glutathione (GSH) metabolism and is highlighted as a potential biomarker and a therapeutic target for enhancing ferroptosis-based cancer therapy.
Xiangfei Xue, Xiao Zhang, Qianjun Zhou et al.
· Molecules and Cells · 0 citations